Based on data from 40 vehicles, 2,655 fuel-ups and 843,228 miles of driving, the 2010 Mercedes-Benz E350 gets a combined Avg MPG of 20.88 with a 0.14 MPG margin of error.

Any Engine Type 3.5L V6 GAS (31) V6 DIESEL (1) V6 GAS (4) Any Body Style Sedan (9) Hatchback (1) Any Submodel Elegance (2) Base (3) Sport (5) 4Matic (22) Other (8)

Below you can see a distribution of the fuel-ups with 152 outliers (5.42%) removed.

Following shows the average MPG of each of the 40 vehicles in the system.

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• Mabel

  2010 Mercedes-Benz E350 4Matic 3.5L V6 GAS Automatic 7 Speed
  Added Aug 2016 • 555 Fuel-ups

  Property of sabinoj

• 22.7 Avg MPG

• My E350

  2010 Mercedes-Benz E350 4Matic 3.5L V6 GAS Automatic 7 Speed
  Added Apr 2024 • 6 Fuel-ups

  Property of TheDesignated1

• 15.2 Avg MPG

• MB E350

  2010 Mercedes-Benz E350 4Matic 3.5L V6 GAS Automatic 7 Speed
  Added Apr 2022 • 74 Fuel-ups

  Property of dhiday

• 18.3 Avg MPG

• 2010 E350

  2010 Mercedes-Benz E350 Sport 3.5L V6 GAS Automatic 7 Speed Sedan
  Added Oct 2017 • 138 Fuel-ups

  Property of jasonhardin09

• 19.4 Avg MPG

• Mercedes-Benz E350

  2010 Mercedes-Benz E350 4Matic 3.5L V6 GAS Automatic 7 Speed Sedan
  Added Apr 2022 • 11 Fuel-ups

  Property of hmholt

• 45.8 Avg MPG

• Koop’s Benz

  2010 Mercedes-Benz E350 4Matic 3.5L V6 GAS Automatic 7 Speed
  Added Oct 2021 • 75 Fuel-ups

  Property of JRKoop

• 19.2 Avg MPG

• My E350

  2010 Mercedes-Benz E350 3.5L V6 GAS Automatic 7 Speed
  Added Mar 2024 • 3 Fuel-ups

  Property of jdm_josh

• 24.4 Avg MPG

• E350

  2010 Mercedes-Benz E350 4Matic 3.5L V6 GAS Automatic 7 Speed Sedan
  Added Sep 2019 • 118 Fuel-ups

  Property of bisric99

• 22.0 Avg MPG

• Merc

  2010 Mercedes-Benz E350 Elegance 3,5L V6 GAS Automatic 7 Speed Sedan
  Added Aug 2020 • 75 Fuel-ups

  Property of topovi

• 16.8 Avg MPG

• E350

  2010 Mercedes-Benz E350 4Matic 3.5L V6 GAS Automatic 7 Speed Sedan
  Added Dec 2023 • 94 Fuel-ups

  Property of jasselmoore

• 21.1 Avg MPG

• MERCEDES

  2010 Mercedes-Benz E350 4Matic 3.5L V6 GAS Automatic 7 Speed Sedan
  Added Jun 2010 • 286 Fuel-ups

  Property of DENNISPS78

• 19.4 Avg MPG

• My E350

  2010 Mercedes-Benz E350 4Matic 3.5L V6 GAS Automatic 7 Speed
  Added Feb 2019 • 67 Fuel-ups

  Property of giobarb

• 19.8 Avg MPG

• Mercedes Benz E350 Sport

  2010 Mercedes-Benz E350 4Matic 3.5L V6 GAS Automatic 7 Speed
  Added Feb 2018 • 123 Fuel-ups

  Property of dcatkc

• 18.1 Avg MPG

• Mercedes Benz

  2010 Mercedes-Benz E350 4Matic 3.5L V6 GAS Automatic 7 Speed
  Added Mar 2017 • 178 Fuel-ups

  Property of redraider6464

• 20.5 Avg MPG

• My E350

  2010 Mercedes-Benz E350 3.5L V6 GAS Automatic 7 Speed
  Added Oct 2017 • 151 Fuel-ups

  Property of JTight

• 20.8 Avg MPG

• My E350

  2010 Mercedes-Benz E350 4Matic 3.5L V6 GAS Automatic 7 Speed
  Added Mar 2018 • 73 Fuel-ups

  Property of Jaromir

• 25.8 Avg MPG

• Mercedes-Benz E350 4Matic

  2010 Mercedes-Benz E350 4Matic 3.5L V6 GAS Automatic 7 Speed
  Added Sep 2016 • 365 Fuel-ups

  Property of Bman508

• 22.2 Avg MPG

• E-350 Benz (W212)

  2010 Mercedes-Benz E350 Sport 3.5L V6 GAS Automatic 7 Speed Sedan
  Added Apr 2018 • 44 Fuel-ups

  Property of RenzaC

• 38.6 Avg MPG

• Mercedes E Class Estate

  2010 Mercedes-Benz E350 Elegance 3.5L V6 GAS Automatic 7 Speed Hatchback
  Added Nov 2018 • 4 Fuel-ups

  Property of Pepe060686

• 15.5 Avg MPG

• 2010 E350

  2010 Mercedes-Benz E350 4Matic 3.5L V6 GAS Automatic 7 Speed Sedan
  Added Nov 2017 • 29 Fuel-ups

  Property of joshuawallace

• 20.3 Avg MPG

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