Based on data from 17 vehicles, 2,021 fuel-ups and 537,477 miles of driving, the 2016 Lexus IS350 gets a combined Avg MPG of 21.13 with a 0.15 MPG margin of error.

Any Engine Type 3.5L V6 GAS (17) Any Body Style Sedan (5) Any Submodel Base (2) F Sport (15)

Below you can see a distribution of the fuel-ups with 26 outliers (1.27%) removed.

Following shows the average MPG of each of the 17 vehicles in the system.

• 2016 Lexus IS350

  2016 Lexus IS350 F Sport 3.5L V6 GAS Automatic 6 Speed
  Added Sep 2017 • 240 Fuel-ups

  Property of akissinger

• 21.2 Avg MPG

• F Sport!

  2016 Lexus IS350 F Sport 3.5L V6 GAS Automatic 6 Speed
  Added Jun 2018 • 271 Fuel-ups

  Property of plasticplant

• 20.4 Avg MPG

• My IS350

  2016 Lexus IS350 F Sport 3.5L V6 GAS Automatic 6 Speed
  Added Jul 2016 • 391 Fuel-ups

  Property of sundevilnation

• 22.4 Avg MPG

• Lexus

  2016 Lexus IS350 3,5L V6 GAS Automatic 8 Speed Sedan
  Added Aug 2018 • 150 Fuel-ups

  Property of KJLRSA

• 19.7 Avg MPG

• Lexus

  2016 Lexus IS350 F Sport 3.5L V6 GAS Automatic 6 Speed Sedan
  Added Aug 2019 • 147 Fuel-ups

  Property of Gomidas2007

• 21.4 Avg MPG

• My IS350

  2016 Lexus IS350 F Sport 3.5L V6 GAS Automatic 8 Speed
  Added Sep 2021 • 27 Fuel-ups

  Property of joshuacoley83

• 16.5 Avg MPG

• My IS350

  2016 Lexus IS350 F Sport 3.5L V6 GAS Automatic 6 Speed
  Added Aug 2019 • 23 Fuel-ups

  Property of bigjollygiant14

• 18.9 Avg MPG

• IS350

  2016 Lexus IS350 3.5L V6 GAS Automatic 6 Speed Sedan
  Added Jan 2017 • 130 Fuel-ups

  Property of JamminJosh

• 17.4 Avg MPG

• Lexus

  2016 Lexus IS350 F Sport 3.5L V6 GAS Automatic 8 Speed Sedan
  Added Feb 2016 • 166 Fuel-ups

  Property of alexduke

• 21.6 Avg MPG

• 2016 Lexus IS350

  2016 Lexus IS350 F Sport 3.5L V6 GAS Automatic 8 Speed
  Added Sep 2016 • 197 Fuel-ups

  Property of PerfectTommy

• 23.5 Avg MPG

• My IS350-Lexi

  2016 Lexus IS350 F Sport 3.5L V6 GAS Automatic 6 Speed
  Added Feb 2019 • 29 Fuel-ups

  Property of btjetman

• 22.0 Avg MPG

• My IS350

  2016 Lexus IS350 F Sport 3.5L V6 GAS Automatic 6 Speed
  Added May 2019 • 11 Fuel-ups

  Property of gasmeup2018

• 21.9 Avg MPG

• 2016 Lexus IS350

  2016 Lexus IS350 F Sport 3.5L V6 GAS Automatic 8 Speed
  Added Mar 2017 • 72 Fuel-ups

  Property of fernandoacevedo

• 19.1 Avg MPG

• 2016 Lexus IS350 AWD F-sport

  2016 Lexus IS350 F Sport 3.5L V6 GAS Automatic 6 Speed Sedan
  Added Oct 2015 • 103 Fuel-ups

  Property of tdesi420

• 21.8 Avg MPG

• Lexus IS350 F sport

  2016 Lexus IS350 F Sport 3.5L V6 GAS Automatic 6 Speed
  Added Sep 2016 • 63 Fuel-ups

  Property of romanoaa

• 22.0 Avg MPG

• Lexus IS350 F-Sport

  2016 Lexus IS350 F Sport 3.5L V6 GAS Automatic 8 Speed
  Added Sep 2016 • 99 Fuel-ups

  Property of PerfectTommy

• 26.0 Avg MPG

• My IS350

  2016 Lexus IS350 F Sport 3.5L V6 GAS Automatic 8 Speed
  Added Dec 2015 • 4 Fuel-ups

  Property of mahende2

• 17.2 Avg MPG