Based on data from 47 vehicles, 3,557 fuel-ups and 1,050,264 miles of driving, the 2010 Lexus IS250 gets a combined Avg MPG of 22.54 with a 0.16 MPG margin of error.

Any Engine Type 2.5L V6 GAS (37) V6 GAS (7) Any Body Style Sedan (7) Convertible (3) Any Submodel C (9) Base (28) Other (10)

Below you can see a distribution of the fuel-ups with 129 outliers (3.50%) removed.

Following shows the average MPG of each of the 47 vehicles in the system.

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• Lexus IS 250

  2010 Lexus IS250 2.5L V6 GAS Automatic 6 Speed
  Added Mar 2017 • 692 Fuel-ups

  Property of amschramm

• 23.9 Avg MPG

• IS

  2010 Lexus IS250 2.5L V6 GAS Automatic 6 Speed
  Added Mar 2019 • 47 Fuel-ups

  Property of mbs

• 19.2 Avg MPG

• IS250

  2010 Lexus IS250 2.5L V6 GAS Automatic 6 Speed Convertible
  Added Jun 2019 • 79 Fuel-ups

  Property of ptobey

• 30.6 Avg MPG

• My IS

  2010 Lexus IS250 2.5L V6 GAS Automatic 6 Speed
  Added Aug 2021 • 205 Fuel-ups

  Property of cainmike

• 21.5 Avg MPG

• My IS250

  2010 Lexus IS250 2.5L V6 GAS Automatic 6 Speed
  Added Nov 2024 • 11 Fuel-ups

  Property of 2025_Silver_Subie

• 24.4 Avg MPG

• IS250

  2010 Lexus IS250 2.5L V6 GAS Automatic 6 Speed Sedan
  Added Jun 2024 • 32 Fuel-ups

  Property of Elkyracer

• 24.8 Avg MPG

• Lexus IS250

  2010 Lexus IS250 IS 250
  Added Sep 2016 • 284 Fuel-ups

  Property of maro254

• 21.2 Avg MPG

• IS250c

  2010 Lexus IS250 C 2.5L V6 GAS Automatic 6 Speed
  Added Feb 2020 • 72 Fuel-ups

  Property of rickandjamie

• 20.7 Avg MPG

• Lexus IS 250

  2010 Lexus IS250 2.5L V6 GAS Automatic 6 Speed
  Added Sep 2016 • 374 Fuel-ups

  Property of sleuthy

• 28.1 Avg MPG

• Lexus IS250

  2010 Lexus IS250 2.5L V6 GAS Automatic 6 Speed
  Added May 2016 • 256 Fuel-ups

  Property of dgclark

• 23.7 Avg MPG

• Lexus IS250

  2010 Lexus IS250 2.5L V6 GAS Automatic 6 Speed Sedan
  Added May 2021 • 51 Fuel-ups

  Property of alexvtr

• 24.1 Avg MPG

• 10 Lexus IS250

  2010 Lexus IS250 2.5L V6 GAS Automatic 6 Speed Sedan
  Added Jan 2019 • 111 Fuel-ups

  Property of igpoobah

• 28.2 Avg MPG

• My IS250

  2010 Lexus IS250 C 2.5L V6 GAS Automatic 6 Speed
  Added May 2024 • 3 Fuel-ups

  Property of txtreefrog

• 165,000.0 Avg MPG

• My IS250

  2010 Lexus IS250 2.5L V6 GAS Automatic 6 Speed
  Added Aug 2024 • 10 Fuel-ups

  Property of phamtony

• 22.4 Avg MPG

• IS250C

  2010 Lexus IS250 C 2.5L V6 GAS Automatic 6 Speed
  Added Aug 2021 • 21 Fuel-ups

  Property of gerardz

• 23.0 Avg MPG

• My IS250

  2010 Lexus IS250 2.5L V6 GAS Automatic 6 Speed
  Added Mar 2024 • 24 Fuel-ups

  Property of achu1362

• 23.2 Avg MPG

• Lexus

  2010 Lexus IS250 C 2.5L V6 GAS Automatic 6 Speed
  Added Sep 2016 • 38 Fuel-ups

  Property of georgechat

• 27.7 Avg MPG

• My IS250

  2010 Lexus IS250 2.5L V6 GAS Automatic 6 Speed
  Added Jan 2024 • 40 Fuel-ups

  Property of vmurcko

• 27.9 Avg MPG

• My IS250

  2010 Lexus IS250 C 2.5L V6 GAS Automatic 6 Speed
  Added Jun 2022 • 35 Fuel-ups

  Property of MDX1

• 11.5 Avg MPG

• IS 250

  2010 Lexus IS250
  Added Apr 2013 • 127 Fuel-ups

  Property of ewilkes

• 27.1 Avg MPG

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