Based on data from 117 vehicles, 13,560 fuel-ups and 3,382,715 miles of driving, the 2006 GMC Sierra 2500 HD gets a combined Avg MPG of 14.25 with a 0.05 MPG margin of error.

Any Engine Type 6.0L V8 GAS (21) 6.6L V8 DIESEL (87) 8.1L V8 GAS (1) V8 DIESEL (3) V8 GAS (3) Any Body Style Sport Utility (1) Extended Cab Pickup (5) Crew Cab Pickup (33) Any Submodel SL (6) WT (6) SLE (30) SLT (68) Other (7)

Below you can see a distribution of the fuel-ups with 471 outliers (3.36%) removed.

Following shows the average MPG of each of the 117 vehicles in the system.

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• My Sierra 2500 HD

  2006 GMC Sierra 2500 HD SLE 6.6L V8 DIESEL Automatic 6 Speed
  Added Feb 2017 • 356 Fuel-ups

  Property of HomerDMAX

• 16.4 Avg MPG

• Tritnee

  2006 GMC Sierra 2500 HD SLE 6.6L V8 DIESEL Automatic 6 Speed
  Added Jul 2024 • 19 Fuel-ups

  Property of Lord_Commander

• 16.1 Avg MPG

• 2006 Sierra 2500 HD

  2006 GMC Sierra 2500 HD SL 6.6L V8 DIESEL Automatic 6 Speed
  Added Sep 2021 • 193 Fuel-ups

  Property of dillyboy

• 16.0 Avg MPG

• My Sierra 2500 HD

  2006 GMC Sierra 2500 HD SLT 6.6L V8 DIESEL Automatic 6 Speed
  Added Nov 2022 • 104 Fuel-ups

  Property of sixsix_tom

• 15.4 Avg MPG

• My Sierra 2500 HD

  2006 GMC Sierra 2500 HD SLT 6.0L V8 GAS Automatic 4 Speed
  Added May 2022 • 81 Fuel-ups

  Property of theminthawk

• 11.5 Avg MPG

• 2006 GMC Sierra 2500HD

  2006 GMC Sierra 2500 HD SLT 6.6L V8 DIESEL Automatic 6 Speed Crew Cab Pickup
  Added Jun 2018 • 684 Fuel-ups

  Property of tkemo648

• 16.1 Avg MPG

• Duramax 2500HD

  2006 GMC Sierra 2500 HD SLT 6.6L V8 DIESEL Automatic 6 Speed Crew Cab Pickup
  Added Aug 2022 • 410 Fuel-ups

  Property of awesomeamerican

• 16.2 Avg MPG

• Patrick 3.0

  2006 GMC Sierra 2500 HD WT 6.0L V8 GAS Automatic 5 Speed Extended Cab Pickup
  Added Mar 2024 • 3 Fuel-ups

  Property of Aeillustration

• 11.2 Avg MPG

• Red Solo Truck

  2006 GMC Sierra 2500 HD Custom Submodel V8 DIESEL
  Added Jun 2012 • 192 Fuel-ups

  Property of helmet

• 15.8 Avg MPG

• DookieMax

  2006 GMC Sierra 2500 HD SLT 6.6L V8 DIESEL Automatic 6 Speed
  Added Jan 2017 • 277 Fuel-ups

  Property of Peen

• 16.6 Avg MPG

• Truck

  2006 GMC Sierra 2500 HD SL 6.6L V8 DIESEL Standard 6 Speed
  Added Mar 2018 • 190 Fuel-ups

  Property of Bacons2018

• 14.1 Avg MPG

• 2006 Duramax

  2006 GMC Sierra 2500 HD SLT 6.6L V8 DIESEL Automatic 6 Speed Crew Cab Pickup
  Added Apr 2018 • 270 Fuel-ups

  Property of oskam6

• 14.0 Avg MPG

• My Sierra 2500 HD

  2006 GMC Sierra 2500 HD SLT 6.6L V8 DIESEL Automatic 6 Speed
  Added Aug 2017 • 420 Fuel-ups

  Property of PrestonL

• 14.5 Avg MPG

• My Sierra 2500 HD

  2006 GMC Sierra 2500 HD SLE 8.1L V8 GAS Automatic 5 Speed
  Added Sep 2022 • 105 Fuel-ups

  Property of firedave654

• 10.1 Avg MPG

• Truck

  2006 GMC Sierra 2500 HD WT 6.6L V8 DIESEL Automatic 6 Speed Crew Cab Pickup
  Added Jul 2015 • 258 Fuel-ups

  Property of gaskippy

• 13.5 Avg MPG

• Truck

  2006 GMC Sierra 2500 HD SLE 6.0L V8 GAS Automatic 4 Speed Crew Cab Pickup
  Added Dec 2018 • 75 Fuel-ups

  Property of Hagfan72

• 10.2 Avg MPG

• Duramax

  2006 GMC Sierra 2500 HD SLT 6.6L V8 DIESEL Automatic 6 Speed Crew Cab Pickup
  Added Oct 2017 • 211 Fuel-ups

  Property of bsneed

• 15.3 Avg MPG

• My Sierra 2500 HD

  2006 GMC Sierra 2500 HD SLE 6.6L V8 DIESEL Automatic 6 Speed
  Added Apr 2023 • 70 Fuel-ups

  Property of joesauto24

• 14.0 Avg MPG

• Quiv

  2006 GMC Sierra 2500 HD SLT 6.6L V8 DIESEL Automatic 6 Speed
  Added Sep 2017 • 266 Fuel-ups

  Property of JordanTr

• 16.1 Avg MPG

• 2500HD

  2006 GMC Sierra 2500 HD SLT 6.6L V8 DIESEL Automatic 6 Speed Crew Cab Pickup
  Added Aug 2018 • 492 Fuel-ups

  Property of hummingbird63012

• 15.3 Avg MPG

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