Based on data from 215 vehicles, 13,281 fuel-ups and 4,158,874 miles of driving, the 2006 Ford F-250 Super Duty gets a combined Avg MPG of 13.15 with a 0.06 MPG margin of error.

Any Engine Type 5.4L V8 GAS (17) 6.0L V8 DIESEL (152) 6.8L V10 GAS (4) GAS (1) L6 DIESEL (1) V8 DIESEL (32) V8 GAS (2) Any Body Style Standard Cab Pickup (2) Extended Cab Pickup (15) Crew Cab Pickup (45) Cab & Chassis - Crew Cab (1) Any Submodel Harley-Davidson Edition (5) XL (14) King Ranch (19) Lariat (64) XLT (72) Other (41)

Below you can see a distribution of the fuel-ups with 518 outliers (3.75%) removed.

Following shows the average MPG of each of the 215 vehicles in the system.

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• F-250 Super Duty

  2006 Ford F-250 Super Duty Lariat 6.0L V8 DIESEL Automatic 5 Speed
  Added Mar 2017 • 67 Fuel-ups

  Property of cjlatl

• 13.9 Avg MPG

• New F-250

  2006 Ford F-250 Super Duty XLT 6.0L V8 DIESEL Automatic 5 Speed
  Added Aug 2020 • 21 Fuel-ups

  Property of ajohn2550

• 12.4 Avg MPG

• Green Machine

  2006 Ford F-250 Super Duty XL 5.4L V8 GAS Standard 6 Speed Extended Cab Pickup
  Added Apr 2020 • 201 Fuel-ups

  Property of cvsack

• 14.3 Avg MPG

• My F-250 Super Duty

  2006 Ford F-250 Super Duty Lariat 6.0L V8 DIESEL Automatic 5 Speed
  Added Feb 2019 • 187 Fuel-ups

  Property of wildcat351

• 14.2 Avg MPG

• 2006 Ford F250

  2006 Ford F-250 Super Duty Lariat 6.0L V8 DIESEL Automatic 5 Speed
  Added Mar 2017 • 243 Fuel-ups

  Property of motoman358

• 14.5 Avg MPG

• My F-250 Super Duty

  2006 Ford F-250 Super Duty Lariat 6.0L V8 DIESEL Automatic 5 Speed
  Added Jan 2021 • 26 Fuel-ups

  Property of kdubois98

• 11.2 Avg MPG

• My F-250 Super Duty

  2006 Ford F-250 Super Duty Lariat 6.0L V8 DIESEL Automatic 5 Speed
  Added May 2021 • 4 Fuel-ups

  Property of brazil

• 15.3 Avg MPG

• My F-250 Super Duty

  2006 Ford F-250 Super Duty XLT 6.0L V8 DIESEL Automatic 5 Speed
  Added Sep 2019 • 67 Fuel-ups

  Property of RJ_Cleelan

• 11.2 Avg MPG

• My F-250 Super Duty

  2006 Ford F-250 Super Duty XLT 6.0L V8 DIESEL Automatic 5 Speed
  Added Feb 2021 • 48 Fuel-ups

  Property of Rocketmedic

• 13.8 Avg MPG

• Power Stroke

  2006 Ford F-250 Super Duty XLT 6.0L V8 DIESEL Automatic 5 Speed Extended Cab Pickup
  Added Mar 2014 • 226 Fuel-ups

  Property of Obadiah

• 13.4 Avg MPG

• F-250 Super Duty 6.0

  2006 Ford F-250 Super Duty XLT 6.0L V8 DIESEL Automatic 5 Speed
  Added Nov 2019 • 98 Fuel-ups

  Property of Leadfoot115

• 12.6 Avg MPG

• My F-250 Super Duty

  2006 Ford F-250 Super Duty Lariat 6.0L V8 DIESEL Automatic 5 Speed
  Added May 2021 • 9 Fuel-ups

  Property of tacomavol1987

• 14.6 Avg MPG

• My F-250 Super Duty

  2006 Ford F-250 Super Duty Lariat 6.0L V8 DIESEL Automatic 5 Speed
  Added Dec 2019 • 61 Fuel-ups

  Property of spartanboy98

• 12.8 Avg MPG

• Ford F-250

  2006 Ford F-250 Super Duty Harley-Davidson Edition 6.0L V8 DIESEL Automatic 5 Speed
  Added Sep 2018 • 39 Fuel-ups

  Property of raceingbatman73

• 13.0 Avg MPG

• White

  2006 Ford F-250 Super Duty XLT 6.0L V8 DIESEL Automatic 5 Speed
  Added Sep 2016 • 439 Fuel-ups

  Property of Captcohen

• 13.6 Avg MPG

• RV Hualer

  2006 Ford F-250 Super Duty XLT 6.0L V8 DIESEL Automatic 5 Speed Extended Cab Pickup
  Added Apr 2019 • 51 Fuel-ups

  Property of robertjamesryan

• 13.6 Avg MPG

• Ford

  2006 Ford F-250 Super Duty Lariat 6.0L V8 DIESEL Automatic 4 Speed Crew Cab Pickup
  Added Sep 2017 • 214 Fuel-ups

  Property of cowboyez

• 14.6 Avg MPG

• Jon's truck

  2006 Ford F-250 Super Duty XLT 6.0L V8 DIESEL Automatic 5 Speed
  Added Mar 2017 • 176 Fuel-ups

  Property of jlifferth

• 15.9 Avg MPG

• F250

  2006 Ford F-250 Super Duty XLT 6.0L V8 DIESEL Automatic 5 Speed Crew Cab Pickup
  Added Apr 2018 • 535 Fuel-ups

  Property of dgtown71

• 17.4 Avg MPG

• Ford F-250 Powerstroke

  2006 Ford F-250 Super Duty Lariat 6.0L V8 DIESEL Automatic 5 Speed Crew Cab Pickup
  Added Aug 2020 • 6 Fuel-ups

  Property of Lordadam

• 14.1 Avg MPG

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