Based on data from 105 vehicles, 8,705 fuel-ups and 2,224,512 miles of driving, the 2010 Lexus RX350 gets a combined Avg MPG of 19.31 with a 0.07 MPG margin of error.

Any Engine Type 3.5L V6 GAS (93) GAS (1) V6 GAS (9) Any Body Style Sport Utility (33) Any Submodel Base (93) Other (12)

Below you can see a distribution of the fuel-ups with 546 outliers (5.90%) removed.

Following shows the average MPG of each of the 105 vehicles in the system.

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• RX350 de Lilian

  2010 Lexus RX350 3.5L V6 GAS Automatic 6 Speed
  Added Oct 2021 • 87 Fuel-ups

  Property of Harst0nV3hic

• 20.4 Avg MPG

• My RX350

  2010 Lexus RX350 3.5L V6 GAS Automatic 6 Speed
  Added Mar 2017 • 294 Fuel-ups

  Property of wetfeetthenovel

• 19.2 Avg MPG

• RX350

  2010 Lexus RX350 3.5L V6 GAS Automatic 6 Speed
  Added Mar 2024 • 39 Fuel-ups

  Property of eoganesyan

• 23.5 Avg MPG

• My RX350

  2010 Lexus RX350 3.5L V6 GAS Automatic 6 Speed
  Added Dec 2018 • 170 Fuel-ups

  Property of thanos007

• 15.4 Avg MPG

• 2010 RX350

  2010 Lexus RX350 3.5L V6 GAS Automatic 6 Speed
  Added Apr 2025 • 14 Fuel-ups

  Property of jesatto

• 22.0 Avg MPG

• 2010 Lexus RX350

  2010 Lexus RX350 3.5L V6 GAS Automatic 6 Speed Sport Utility
  Added Feb 2024 • 47 Fuel-ups

  Property of TheMightyPC

• 25.9 Avg MPG

• 1 - My RX350

  2010 Lexus RX350 3.5L V6 GAS Automatic 6 Speed
  Added Aug 2024 • 39 Fuel-ups

  Property of journeyfan91

• 21.0 Avg MPG

• My RX350

  2010 Lexus RX350 3.5L V6 GAS Automatic 6 Speed
  Added Feb 2023 • 91 Fuel-ups

  Property of xtinar

• 18.1 Avg MPG

• Darrien-Raecca

  2010 Lexus RX350 3.5L V6 GAS Automatic 6 Speed
  Added Mar 2017 • 148 Fuel-ups

  Property of mysuv

• 13.7 Avg MPG

• My RX350

  2010 Lexus RX350 3.5L V6 GAS Automatic 6 Speed
  Added Jan 2019 • 177 Fuel-ups

  Property of EscapeFromML

• 18.8 Avg MPG

• 2010 Lexus RX 350

  2010 Lexus RX350 3.5L V6 GAS Automatic 6 Speed Sport Utility
  Added Oct 2021 • 85 Fuel-ups

  Property of crishchun

• 19.6 Avg MPG

• 2589-A9

  2010 Lexus RX350 3.5L V6 GAS Automatic 6 Speed Sport Utility
  Added Apr 2017 • 318 Fuel-ups

  Property of kittyfish

• 21.0 Avg MPG

• My RX350

  2010 Lexus RX350 3.5L V6 GAS Automatic 6 Speed
  Added Jan 2023 • 71 Fuel-ups

  Property of Ericxu

• 19.2 Avg MPG

• My RX350

  2010 Lexus RX350 3.5L V6 GAS Automatic 6 Speed
  Added Sep 2022 • 82 Fuel-ups

  Property of pootie

• 21.0 Avg MPG

• Lexus

  2010 Lexus RX350 3.5L V6 GAS Automatic 6 Speed Sport Utility
  Added Aug 2024 • 8 Fuel-ups

  Property of WSGutowski

• 26.7 Avg MPG

• 2010 Lexus RX350

  2010 Lexus RX350 3.5L V6 GAS Automatic 6 Speed Sport Utility
  Added Aug 2010 • 249 Fuel-ups

  Property of wkwan

• 21.0 Avg MPG

• RX350

  2010 Lexus RX350 3.5L V6 GAS Automatic 6 Speed
  Added Mar 2017 • 425 Fuel-ups

  Property of travelchamp

• 18.8 Avg MPG

• RX

  2010 Lexus RX350 3.5L V6 GAS Automatic 6 Speed Sport Utility
  Added Apr 2017 • 338 Fuel-ups

  Property of N4TECguy

• 19.9 Avg MPG

• Lexus

  2010 Lexus RX350 3.5L V6 GAS Automatic 6 Speed Sport Utility
  Added Apr 2018 • 207 Fuel-ups

  Property of WARoche

• 20.0 Avg MPG

• Beth Lexus RX350

  2010 Lexus RX350 3.5L V6 GAS Automatic 6 Speed
  Added Sep 2016 • 83 Fuel-ups

  Property of designeng

• 21.5 Avg MPG

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